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| 文献摘要：膳食摄入的类胡萝卜素在心血管保健上的抗氧化和抗炎症作用 |
| 发布时间：2015/12/8 13:47:21 阅读次数：264 |
当前，以动脉硬化为代表的心血管疾病在发达国家有最高的发病率和致死率。鉴于动脉硬化产生炎症的特质，已经开展了动脉壁抗炎活性物质的发掘工作，这些物质能够能够对健康产生有益的作用。由于类胡罗卜素能够清除自由基、提高低密度脂蛋白胆固醇的抗氧化作用，因此一些文章研究了膳食补充类胡罗卜素对心血管疾病的作用。不过，文献资料却相互矛盾：尽管一些研究发现膳食补充类胡罗卜素与降低心血管疾病有正相关的关系，但是其它研究并没有发现二者之间有任何的正相关性，甚至一些研究还发现类胡罗卜素具有促进氧化的作用。本文旨在通过文献数据说明膳食补充类胡萝卜素对心血管疾病的作用，从而促使我们关注饮食中这些类胡萝卜素（β-胡萝卜素，α-胡萝卜素，β-隐黄质，番茄红素，叶黄素，玉米黄质和虾青素）。
Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular care
Cardiovascular disease related to atherosclerosis represents nowadays the largest cause of morbidity and mortality in developed countries. Due to inflammatory nature of atherosclerosis, several studies had been conducted in order to search for substances with anti-inflammatory activity on arterial walls, able to exert beneficial roles on health. Researches investigated the role of dietary carotenoids supplementation on cardiovascular disease, due to their free radicals scavenger properties and their skills in improving low-density lipoprotein cholesterol resistance to oxidation. Nevertheless, literature data are conflicting: although some studies found a positive relationship between carotenoids supplementation and cardiovascular risk reduction, others did not find any positive effects or even prooxidant actions. This paper aimed at defining the role of carotenoids supplementation on cardiovascular risk profile by reviewing literature data, paying attention to those carotenoids more present in our diet (β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein, zeaxanthin, and astaxanthin).
Ciccone MM, Cortese F, Gesualdo M, Carbonara S, Zito A, RicciG, De Pascalis F, Scicchitano P, Riccioni G.
Mediators Inflamm. 2013, 2013:782137.
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